On today's episode we talk with popular guest Dr. Chris Booth of Queen's University in Kingston, Ontario, Canada about mapping out a career path after medical school and about his new paper out now in JAMA Oncology titled "Evolution of the Randomized Clinical Trial in the Era of Precision Oncology".

Today we interview Dr. Ghulam Rehman Mohyuddin of Kansas University Medical Center on his new paper out now in The Lancet Haematology titled "Quality of control groups in randomised trials of multiple myeloma enrolling in the USA: a systematic review".

Today we sit down with Dr. Matthew Smith, an associate professor in the Northeastern University Department of Philosophy and Religion, to discuss the morality and philosophical backbone behind COVID-19 vaccine distribution and how we should define equity; cancel culture and its historical longevity; and the impossibility (at least in the USA) of Zero COVID-19.

For today's episode we have a short monologue in remembrance of famed cancer researcher Dr. José Baselga.

Today we interview Dr. Bob Wachter, the Chair of the Department of Medicine at University of California San Francisco. We talk about a wide range of topics including medicine, leadership, SARS-CoV-2, and social media.

On today's episode we interview Youyang Gu, an independent data scientist who created some of the most models of the COVID-19 pandemic. He talks us through how he made the projections. His work is available on his website: https://covid19-projections.com/

On today's SHORT episode, we talk about censorship, Facebook, Twitter, and the "evildoer" Dr. Marty Makary.

Today we interview Dr. Robert Freudenthal, a psychiatrist in training at Barnet Enfield and Haringey Mental Health Trust in London, UK. We talk abut the power of the state and its role in public health policy. We focus specifically on how governments worldwide have responded to the COVID-19 pandemic, from extreme lockdowns to harm reduction advisories. We discuss how policy can be medical overreach as well as how it interplays with the criminal justice system and racial and class inequities. Finally, we discuss censorship and the need for trust and honesty in messaging.

Today we interview Dr. Luc Morris of Memorial Sloan Kettering Cancer Center on his new paper out now in JAMA Oncology titled "Response Rates to Anti-PD-1 Immunotherapy in Microsatellite-Stable Solid Tumors With 10 or More Mutations per Megabase".

Today we interview Dr. Monica Gandhi, Associate Division Chief of the Division of HIV, Infectious Diseases, and Global Medicine at UCSF/ San Francisco General Hospital, and medical director of the HIV Clinic at SFGH, on COVID-19 interventions. We talk about results from the vaccine studies and how vaccination is perceived by the public. We talk about her new paper out now in The Lancet Infectious Disease on the importance of non-pharmaceutical interventions (masking, social distancing, ventilation, hand-washing) in controlling COVID-19. We also talk about the stark difference between messaging created from the point of view of an epidemiologist vs the public health messaging that frontline health care workers deliver directly to patients. We end the interview by talking about schools and the need to re-open them.

Today we interview Dr. Tracy Høeg on her new paper and her ongoing research into COVID-19 transmission in K-12 schools in Wisconsin, USA. Dr. Høeg is an epidemiologist and an interventional sports and medicine spine specialist at Northern California Orthopaedic Associates. Her paper is titled "COVID-19 Cases and Transmission in 17 K-12 Schools - Wood County, Wisconsin, August 31-November 29, 2020" and is published in the CDC's Morbidity and Mortality Weekly Report.

On today's episode we interview Dr. Bryan Carmody, commonly known as the Sheriff of Sodium. He's a pediatric nephrologist at Children's Hospital of the King's Daughters in Virginia. We talk with him about the USMLE Steps (Step 1, Step 2, and Step 2 CS), their usefulness, their origins, and how to reform them. We also break down and discuss the inner workings of residency matching and the M.D. and D.O. designations.

Today we sit down with Dr. Alex John London, the Clara L. West Professor of Ethics and Philosophy and Director of the Center for Ethics and Policy at Carnegie Mellon University, to discuss the role of philosophy, COVID-19 exceptionalism, and various aspects of COVID-19 health policy including masking, vaccination, and schools.

On today’s episode we review the findings of the Beat AML study as published in Nature Medicine in an article titled “Precision medicine treatment in acute myeloid leukemia using prospective genomic profiling: feasibility and preliminary efficacy of the Beat AML Master Trial”.

For today's episode, we sit down with Drs. Ade Adamson of the University of Texas at Austin Dell Medical School and Ben Mazer of Johns Hopkins Hospital to discuss their new paper out now in the New England Journal of Medicine titled "The Rapid Rise in Cutaneous Melanoma Diagnoses". It's one of the best papers you'll read all year.

On today's episode we're joined by geneticist Dr. Francois Balloux, the Director of the University College London Genetics Institute and professor of computational systems biology, on pandemic mitigation, SARS-CoV-2 variants, how news and social media amplify fear over fact, opening schools, lethality and risk, the origin of SARS-CoV-2, COVID-19 vaccine efficacy and vaccine escape, and more!

On today's episode we feature an in-depth interview with Dr. Julia Marcus (Associate Professor at Harvard Medical School) and Dr. Stefan Baral (Associate Professor at Johns Hopkins Bloomberg School of Public Health), two infectious disease epidemiologists, on public health messaging around COVID-19 -- what we're getting right and where we're going terribly wrong.

On today's episode we sit down with Dr. Chris Booth of Queen's University in Kingston, Ontario, Canada to discuss his new paper out now in JAMA Oncology titled "An Analysis of Contemporary Oncology Randomized Clinical Trials From Low/Middle-Income vs High-Income Countries". We also talk about how COVID-19 has affected oncology research. We touch, too, on the topic of evaluating how you spend your time and prioritizing your research.

On today's episode we are joined by Jacob Hale Russell, an Associate Professor of Law at Rutgers Law School. We discuss his forthcoming book on skepticism, elites, and expertise, as well as his article out now on StatNews about the myth of COVID-19 denial. We talk about anti-intellectualism and how science ought to be debated in the era of trade-offs and COVID-19.

On today's episode we sit down with Dr. Arye Elfenbein, a cardiologist and "doctorpreneur " to interview him on the bio-tech company he recently co-founded: Wildtype. Wildtype manufactures ex-vivo fish meat for human consumption in fulfillment of their mission to create the cleanest, most sustainable seafood.