4.48 The Truth About RCTs In Cancer Medicine
Pragmatic vs Ideal, Surrogate vs. Hard Endpoints; Time it takes; Ethics; Control arms; Purpose; I cover it all here.
4.47 Malignant Book Club w/ Dr. Olivier Part 2 of 9
In this book club we discuss Chapters 2 and 3 of Malignant, covering Surrogates and their role in Oncology.
4.46 - Cancer Monologue and Lecture #5 from VP's Class on How to Appraise Medical Literature
This is a brief monologue with Dr. Timothee Olivier, and the audio from a class I taught on RCTs-- when are they needed in biomedicine
4.45 - Malignant Book Club w/ Dr. Olivier Part 1 of 9
Here is the first of a 9 part series on Malignant Book Club with Timothee Olivier from Switzerland
We cover cost of drugs, and intro to cancer drug policy
4.44 Cost Of Cancer Drugs - Basics In Cancer Drug Policy
Vinay Prasad lectures on basics on cancer drug policy
4.43 VKPrasad Lab Update Part 2 With Timothee Olivier
I am back with Timothee Olivier from Geneva Switzerland to discuss Part 2 of our laboratory work. Can oncologists criticize RCTs?
4.42 Timothee Olivier, Geneva in the first Installment of VKPrasad Lab updates
Timothee Olivier from Geneva Hospital Switzerland joins me for the first in a series of episodes on updates from VKPrasad laboratory, where we discuss cancer drugs & policy & evidence
4.41 The Mask Debacle with Jacob Hale Russell
Jacob Hale Russell is back from Rutgers law to talk about his new piece in Tablet Magazine.
4.40 H Gilbert Welch - Melanoma Screening; Blood Based Cancer testing; Lung CA screening
A discussion about the excesses of testing with Gil Welch
4.39 Dr Zeb Jamrozik, ID ethicist, practicing doctor, great thinker
I am joined for my 4th conversation with Zeb. This is a far reaching conversation where we discuss mandates, vaccines, masking, and why evidence based medicine still has something to offer.
4.38 COVID-19: Boosters for Adults and Teens, Paul Offitt, Testing, Myocarditis, Campus Restrictions
We're back this week with a collection of monologues! We talk about a Paul Offit quote, COVID boosters for adults and kids, COVID testing, whether this is a pandemic of the unvaccinated, myocarditis and pericarditis, college campus restrictions, and more!
4.37 MEMOIR & The Emperor Has No Clothes (a Critique of Cancer Care) with Dr. Christopher Booth
Today we have a short discussion for you of the MEMOIR study, published in The Lancet Oncology: "Effect of immunotherapy time-of-day infusion on overall survival among patients with advanced melanoma in the USA (MEMOIR): a propensity score-matched analysis of a single-centre, longitudinal study". We also have a special treat for you: a lecture Dr. Chris Booth of Queen's University, Kingston, Ontario, Canada recently gave titled "The Emperor Has No Clothes", a critique of the current state of cancer care.
4.36 Where Are We Now with COVID-19? with Dr. John Ioannidis
Today we have an in-depth, in-person interview with Dr. John Ioannidis of Stanford University. We ask him: where are we now with COVID-19?
4.35 Omicron, Travel Bans, Masks, Vaccine Mandates with Dr. Zeb Jamrozik
Dr. Zeb Jamrozik, an infectious disease bioethicist at the Monash Bioethics Centre and the University of Oxford, is back again! We discuss Omicron, travel bans, masks, vaccine mandates, and more.
4.34 - ASH Lymphoma Updates: POLARIX, ZUMA 7, BELINDA w/ Papa Heme and DRG
David Russler-Germain and Papa Heme join VP to discuss the hottest ASH lymphoma papers: POLARIX and 2 CAR-T trials (ZUMA-7 & BELINDA)
4.33 Melanoma: Tebentafusp, Stage Migration, Adjuvant Therapy, Training with Dr. Adil Daud
We have an in-person interview for you today! We sit down with Dr. Adil Daud of UCSF to talk all things melanoma. We cover Tebentafusp, nodal dissection, the Will Rogers phenomenon and the effect of stage migration on clinical trials as imaging advances, adjuvant vs I/O, academic training vs apprenticeship for budding oncologists, and more!
4.32 Oral Azacitidine for AML and Nelarabine for T-ALL with Dr. Bernard Marini
We're back with a hematology/oncology heavy episode! We talk about oral azacitidine for acute myeloid leukemia (AML) and nelarabine for T-cell acute lymphoblastic leukemia (T-ALL) with Dr. Bernie Marini, a Clinical Pharmacist Specialist in Hematology and Associate Professor at University of Michigan Medicine.
4.31 Neoadjuvant Radiation Therapy in Pancreatic Adenocarcinoma with Dr. William Hall
Today we interview Dr. Bill Hall, Associate Professor of Radiation Oncology and Surgery at Medical College of Wisconsin, on his new paper out now in the Journal of Clinical Oncology titled "Value of Neoadjuvant Radiation Therapy in the Management of Pancreatic Adenocarcinoma".
4.30 COVID in Children and the US FDA Vaccine Advisory Committee with Dr. Cody Meissner
Today we interview Dr. Cody Meissner, Chief of the Division of Pediatric Infectious Disease and Professor of Pediatrics at Tufts University School of Medicine. Dr. Meissner is also a member of the US FDA Vaccine Advisory Committee. We talk about the affect of school closures on the health of children, the evidence base for COVID vaccine mandates in children, and the nuance surrounding all of it.
4.29 Scientific and Ethical Failures of COVID-19 with Dr. Zeb Jamrozik
Dr. Zeb Jamrozik, an infectious disease bioethicist at the Monash Bioethics Centre and the University of Oxford, is back by popular demand! We talk about the failures, both scientific and ethical, of the COVID-19 pandemic.